首页 学报新闻学报概况编委会专家库学术影响投稿指南审核流程标准规范下载专区投诉邮箱联系我们EngLish
 位置:首页 >> 正文
不同剂型硝磺草酮及其原药对斑马鱼的
急性毒性评价
作者: 宋世明1 陈兆杰1 吴秋榕1 李远富1  程1 赖开平2 谭辉华1 李雪生1* 
单位: (1广西大学 农药与环境毒理研究所/广西农业环境与农产品安全重点实验室培育基地 南宁 530004  
关键词: 斑马鱼 硝磺草酮 剂型 原药 急性毒性 
分类号:S965.819
出版年,卷(期):页码:2017,48(8):1518-1523
摘要:

【目的】评价不同剂型硝磺草酮及其原药对斑马鱼的急性毒性作用,为硝磺草酮的环境生态风险评估提供基础数据,同时为其安全用药提供参考依据。【方法】采用静态法测定不同剂型硝磺草酮及其原药对斑马鱼的急性毒性作用, 并参照化学农药环境安全评价试验准则(GB/T 31270.12-2014),对各供试药剂对斑马鱼96 h的半致死浓度(96 h-LC50)的毒性等级进行划分。【结果】相同染毒时间下,不同剂型硝磺草酮及其原药对斑马鱼的LC50不同。其中,10%硝磺草酮悬浮剂对斑马鱼的96 h-LC50(95%置信限)最低,为6.70(5.18~8.15)mg a.i./L;其次为10%硝磺草酮可分散油悬浮剂和75%硝磺草酮悬水分散粒剂,对斑马鱼的96 h-LC50(95%置信限)分别为10.89(9.29~12.43)和38.97(30.83~47.51)mg a.i./L;98%硝磺草酮原药对斑马鱼的96 h-LC50最高,大于1.00×102 mg a.i./L。依据化学农药环境安全评价试验准则(GB/T 31270.12-2014)进行判定,10%硝磺草酮悬浮剂对斑马鱼的急性毒性为中毒,其他3种为低毒,毒性排序为:10%硝磺草酮悬浮剂>10%硝磺草酮可分散油悬浮剂>75%硝磺草酮水分散粒剂>98%硝磺草酮原药。【结论】不同剂型硝磺草酮及原药对斑马鱼的急性毒性存在明显差异,其毒性排序为:悬浮剂>可分散悬浮剂>水分散粒剂>原药。因此,田间生产时应合理选择农药产品的剂型,并严格控制施药剂量,尽可能减少药剂进入水域环境对鱼类等水体生物造成影响。

【Objective】The aim of the present study was to evaluate the acute toxicity of mesotrione in different formulations and technical materials to zebrafish, provide basic data for environmental ecological risk assessment for mesotrione. At the same time, it could provide reference for rational use of this pesticide. 【Method】Acute toxicity of mesotrione in different formulations and technical materials to zebrafish was evaluated using static test. Toxicity levels of median lethal concentrationto zebrafish in 96 h(96 h-LC50) for the tested pesticides were divided based on Experimental Guideline for Environmental Safety Evaluation of Chemical Pesticides(GB/T 31270.12-2014). 【Result】Under the same exposure time, LC50 of mesotrione in different formulations and technical materials to zebrafish was different. 96 h-LC50(95% confidence limit) of 10% mesotrione oil dispersion(OD) was the lowest[6.70(5.18~8.15)mg a.i./L], followed by 10% mesotrione suspension concentrate(SC), and 75% mesotrione water dispersible granule(WDG) which were 10.89(9.29-12.43) and 38.97(30.83-47.51) mg a.i./L respectively. 96 h-LC50 of 98% mesotrione technical material(TM) to zebrafish was the largest, more than 1.00×102 mg a.i./L. According to the Experimental Guideline for Environmental Safety Evaluation of Chemical Pesticides(GB/T 31270.12-2014), the toxicity of 10% mesotrione SC to zebrafish was moderate, while the others were low. The rank of toxicity was: 10% mesotrione SC>10% mesotrione OD>75% mesotrione WDG>98% mesotrione TM. 【Conclusion】Acute toxicity of mesotrione in different formulations and technical materials to zebrafish is different, the rank is as follows: mesotrione SC>mesotrione OD>mesotrione WDG>mesotrione TM. Therefore, in field cultivation, the formulations of pesticide should be selected accordingly, and the application dosage should be controlled to reduce the negative influence on fish caused by pesticides entering water area environment.

基金项目:
国家重点研发计划项目(2016YFD0201208-4);广西重点实验室培育基地建设项目(桂科基字[2016]133号)
作者简介:
*为通讯作者,李雪生(1977-),博士,副教授,主要从事农药残留与环境安全研究工作,E-mail:lxsnngx@163.com。宋世明(1990-),主要从事农药残留与环境安全研究工作,E-mail:1040830296@qq.com
参考文献:
服务与反馈:
文章下载】【加入收藏
总浏览数:7400669 今日总人数: 4276
主办:广西农业科学院    地址:广西南宁市大学东路174号   邮政编码:530007  
电话:(+86)-771-3243905; (+86)-771-3244920   电子邮箱:gxny@163.net  
Copyright © 2011 Nfnyxb.com, All Rights Reserved  版权所有©2011《南方农业学报》编辑部